Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27621632 | 1.00 | LMNA (0.33) | LMNAL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL18398614 | 1.00 | LMNA (0.33) | LMNAL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL1766146 | 0.97 | BTK (0.33) | LMNAL3MBTL1SMN1; SMN2DPP4BTK | |
| SCHEMBL28590963 | 0.97 | BTK (0.33) | LMNAL3MBTL1SMN1; SMN2DPP4BTK | |
| SCHEMBL16096263 | 0.97 | BTK (0.33) | LMNAL3MBTL1SMN1; SMN2DPP4BTK | |
| SCHEMBL1766144 | 0.97 | BTK (0.33) | LMNAL3MBTL1SMN1; SMN2DPP4BTK | |
| SCHEMBL28861016 | 0.85 | GBA1 (0.33) | LMNADPP4BTK | |
| SCHEMBL27895229 | 0.81 | GSR (0.42) | LMNAL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL27919816 | 0.81 | CYP19A1 (0.40) | LMNAL3MBTL1MEN1MAPTKMT2A | |
| SCHEMBL16995324 | 0.77 | CHRM2 (0.42) | MEN1KMT2AMMP2MMP9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121562-A | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2021-07-16 | — | — | CN | disclosed |
| CN-105658642-A | Fibroblast growth factor receptor inhibitors | 蓝图药品公司 | 2016-06-08 | — | — | CN | disclosed |