Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.60 |
| ▸ | BCR | P11274 | 4/20 | 0.60 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 4/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2616948 | 0.92 | ABL1 (0.59) | ABL1BCRLCKPRKCARET | |
| Hydrochloric Acid SCHEMBL5548680 | 0.91 | ABL1 (0.58) | ABL1BCRLCKPRKCARET | |
| SCHEMBL22793758 | 0.79 | ABL1 (0.70) | ABL1BCRPRKCARETMEN1 | |
| SCHEMBL17713569 | 0.79 | RET (0.56) | ABL1BCRLCKRETNPC1 | |
| SCHEMBL4893292 | 0.78 | ABL1 (0.65) | ABL1BCRLCKPRKCARET | |
| Pyridine SCHEMBL28228170 | 0.76 | PLA2G7 (0.44) | ABL1BCRNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7601457 | 0.76 | ABL1 (0.78) | ABL1BCRLCKPRKCARET | |
| SCHEMBL2580846 | 0.76 | ABL1 (0.74) | ABL1BCRLCKPRKCARET | |
| SCHEMBL24011026 | 0.76 | RAD52 (0.55) | ABL1BCRLCKMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5205211 | 0.75 | ABL1 (0.76) | ABL1BCRLCKPRKCARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102775389-B | Preparation method of N-substituted-4-(7-chloro-quinoline -4-amino)-benzamide derivatives, and application thereof | UNIV HUAQIAO | 2014-12-17 | — | — | CN | claimed |
| CN-102775389-A | Preparation method of N-substituted-4-(7-chloro-quinoline -4-amino)-benzamide derivatives, and application thereof | UNIV HUAQIAO | 2012-11-14 | — | — | CN | claimed |
| CN-116574088-A | 6-trifluoromethyl-1, 2, 4-triazene-3-amide compound, and preparation method and application thereof | 天津大学 | 2023-08-11 | — | — | CN | disclosed |
| CN-102775389-B | Preparation method of N-substituted-4-(7-chloro-quinoline -4-amino)-benzamide derivatives, and application thereof | UNIV HUAQIAO | 2014-12-17 | — | — | CN | disclosed |
| CN-103353510-A | Application of anti-tumor drug on nude-mouse transplanted human-tumor model test | UNIV HUAQIAO | 2013-10-16 | — | — | CN | disclosed |
| CN-102775389-A | Preparation method of N-substituted-4-(7-chloro-quinoline -4-amino)-benzamide derivatives, and application thereof | UNIV HUAQIAO | 2012-11-14 | — | — | CN | disclosed |