Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | GPR3 | P46089 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbazole SCHEMBL27823425 | 1.00 | ALDH1A1 (0.52) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Norharmane SCHEMBL28497734 | 0.88 | CHUK (0.66) | ALDH1A1GPR3HSD17B10KDM4EGABRP | |
| SCHEMBL4445836 | 0.76 | MAOA (0.38) | AHRSMN1; SMN2MAOAMAOBLMNA | |
| SCHEMBL28234789 | 0.76 | NPC1 (0.31) | ALDH1A1KDM4EHPGDSMN1; SMN2MAOA | |
| Naphthalene SCHEMBL27552802 | 0.76 | CYP2A6 (0.38) | — | |
| SCHEMBL19066780 | 0.76 | NPC1 (0.31) | ALDH1A1KDM4EHPGDSMN1; SMN2MAOA | |
| Naphthalene SCHEMBL19066813 | 0.76 | CYP2A6 (0.38) | — | |
| Carbazole SCHEMBL10356293 | 0.75 | ALDH1A1 (0.74) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Carbazole SCHEMBL297671 | 0.74 | ALDH1A1 (0.93) | ALDH1A1GPR3HSD17B10AHRKDM4E | |
| Biphenyl SCHEMBL19379588 | 0.74 | ALDH1A1 (0.41) | ALDH1A1HSD17B10KDM4EGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299398-A | It is a kind of that there is quinazoline derivant and its pharmaceutical applications of the antitumor activity containing carbazole | 苏州华珍医药科技有限公司 | 2018-07-20 | — | — | CN | claimed |
| CN-103145742-B | Chiral oxazoline zinc complex | LUO MEI | 2015-04-15 | — | — | CN | disclosed |
| CN-103145742-A | Chiral oxazoline zinc complex | LUO MEI | 2013-06-12 | — | — | CN | disclosed |
| CN-103130823-A | Chiral oxazolinyl zinc complex | LUO MEI | 2013-06-05 | — | — | CN | disclosed |
| CN-103012447-A | Chiral oxazoline zinc complex | LUO MEI | 2013-04-03 | — | — | CN | disclosed |