Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896421 | 0.85 | KMT2A (0.42) | KMT2AMEN1SIGMAR1GAAALDH1A1 | |
| SCHEMBL27879623 | 0.81 | KMT2A (0.48) | KMT2AMEN1SIGMAR1GAAALDH1A1 | |
| SCHEMBL27879637 | 0.80 | CTSS (0.42) | KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL27896420 | 0.72 | NAPRT (0.42) | SIGMAR1ALDH1A1PARP1KDM4E | |
| SCHEMBL28054810 | 0.71 | PIK3CD (0.55) | — | |
| SCHEMBL13166880 | 0.70 | ALDH1A1 (0.62) | KMT2AMEN1SIGMAR1GAAALDH1A1 | |
| SCHEMBL27879627 | 0.69 | VHL (0.65) | KMT2A | |
| SCHEMBL27896445 | 0.69 | ATM (0.30) | — | |
| SCHEMBL5679866 | 0.66 | KMT2A (0.74) | KMT2AMEN1SIGMAR1GAAALDH1A1 | |
| SCHEMBL2236754 | 0.65 | KMT2A (0.72) | KMT2AMEN1SIGMAR1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791693-B | Hepatitis c virus inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2016-04-13 | — | — | CN | claimed |
| CN-102791693-A | Hepatitis c virus inhibitors | BRISTOL MYERS SQUIBB CO | 2012-11-21 | — | — | CN | claimed |