Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49308 | 0.82 | KEAP1 (0.61) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| Iodide SCHEMBL19990734 | 0.80 | KEAP1 (0.59) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL31243299 | 0.80 | KEAP1 (0.59) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| Hydrochloric Acid SCHEMBL3211155 | 0.80 | KEAP1 (0.59) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| Bromide SCHEMBL22401520 | 0.80 | KEAP1 (0.59) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| SCHEMBL27759423 | 0.80 | KEAP1 (0.59) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| Ammonia Solution, Strong SCHEMBL9173305 | 0.80 | KEAP1 (0.59) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| Carbamic Acid SCHEMBL27524114 | 0.77 | KDM4E (0.65) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| SCHEMBL28017457 | 0.77 | KEAP1 (0.61) | KEAP1RECQLALDH1A1HPGDCYP3A4 | |
| SCHEMBL24163246 | 0.76 | HTR6 (0.47) | KEAP1RECQLALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101511938-B | Crosslinkable aramid copolymers | TEIJIN ARAMID BV | 2012-10-10 | — | — | CN | disclosed |