Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 13/20 | 1.00 |
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 1/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9690067 | 0.80 | GAA (1.00) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL7043304 | 0.78 | GAA (0.64) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL4324931 | 0.77 | ALDH1A1 (0.63) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL27789604 | 0.74 | GAA (0.72) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL667827 | 0.74 | CA2 (0.67) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL238488 | 0.74 | GAA (1.00) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL4858206 | 0.72 | TSHR (0.57) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL12847204 | 0.69 | GAA (0.52) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL28916359 | 0.68 | CA2 (0.60) | GAAMAPTALDH1A1LMNAALOX12 | |
| SCHEMBL163118 | 0.68 | ALDH1A1 (0.61) | GAAMAPTALDH1A1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102977014-B | New quinoline compounds and uses thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-01-07 | — | — | CN | disclosed |
| CN-102977014-A | New quinoline compounds and uses thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-03-20 | — | — | CN | disclosed |