Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL169547 | 0.91 | — | — | |
| SCHEMBL28183604 | 0.88 | — | — | |
| Pyruvate SCHEMBL27849498 | 0.74 | — | — | |
| Acetone SCHEMBL5346221 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRFFAR3TDP1THPO | |
| Acetic Acid SCHEMBL15689725 | 0.73 | FFAR3 (0.64) | ALDH1A1TSHRFFAR3TDP1THPO | |
| Oxalic Acid SCHEMBL9316610 | 0.73 | — | — | |
| Acetic Acid SCHEMBL36929 | 0.73 | — | — | |
| Acetic Acid SCHEMBL3295221 | 0.73 | FFAR3 (0.64) | ALDH1A1TSHRFFAR3TDP1THPO | |
| Acetic Acid SCHEMBL15090782 | 0.73 | FFAR3 (0.64) | ALDH1A1TSHRFFAR3TDP1THPO | |
| Oxalic Acid SCHEMBL29749157 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TSHRFFAR3TDP1THPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004139-B | Method for synthesizing propionic acid by ethanol carbonyl under low water content | 华东理工大学 | 2022-09-02 | — | — | CN | disclosed |
| CN-102794198-A | Preparation method of catalyst for synthesizing propionic acid by ethanol carbonylation, and application thereof | JIANGSU SUOPU GROUP CO LTD | 2012-11-28 | — | — | CN | disclosed |