Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.43 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.54 |
| ▸ | PNMT | P11086 | 2/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27458904 | 0.95 | IDO1 (0.54) | IDO1PNMTTAAR1LMNATSHR | |
| Acetone SCHEMBL28689547 | 0.87 | RAB9A (0.48) | IDO1PNMTTAAR1PKMNPC1 | |
| Bromide SCHEMBL23881740 | 0.75 | TAAR1 (0.58) | IDO1PNMTTAAR1LMNATSHR | |
| SCHEMBL6740216 | 0.75 | TAAR1 (0.71) | IDO1PNMTTAAR1KMT2ALMNA | |
| SCHEMBL672407 | 0.75 | IDO1 (0.62) | IDO1PNMTTAAR1LMNATSHR | |
| SCHEMBL29519238 | 0.75 | IDO1 (0.62) | IDO1PNMTTAAR1LMNATSHR | |
| Hydrochloric Acid SCHEMBL1014616 | 0.74 | IDO1 (0.54) | IDO1PNMTTAAR1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL30719147 | 0.74 | IDO1 (0.54) | IDO1PNMTTAAR1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11231145 | 0.74 | IDO1 (0.54) | IDO1PNMTTAAR1KMT2ALMNA | |
| SCHEMBL126469 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113866292-B | Method for measuring content of o-chlorobenzyl magnesium chloride | 河北威远生物化工有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-110590499-B | Continuous reaction device and synthesis method of prothioconazole intermediate | 泰州百力化学股份有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-113866292-A | Method for measuring content of o-chlorobenzyl magnesium chloride | 河北威远生物化工有限公司 | 2021-12-31 | — | — | CN | claimed |
| CN-109928987-B | Method for preparing o-chlorobenzyl magnesium chloride compound | 北京颖泰嘉和生物科技有限公司 | 2021-12-21 | — | — | CN | claimed |
| CN-110590499-A | Continuous reaction device and synthesis method of prothioconazole intermediate | 泰州百力化学股份有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-110483243-A | A kind of 1-(2- chlorphenyl) -2-(1- chlorine cyclopropyl) the chloro- 2- propyl alcohol of -3- preparation method | XIAN MODERN CHEMISTRY RES INST | 2019-11-22 | — | — | CN | claimed |
| CN-109928987-A | The method for preparing o-chlorobenzyl magnesium chloride class compound | 北京颖泰嘉和生物科技有限公司 | 2019-06-25 | — | — | CN | claimed |
| CN-106279216-A | A kind of synthesis way of o-chlorobenzyl magnesium chloride | 海正化工南通股份有限公司 | 2017-01-04 | — | — | CN | claimed |
| CN-113866292-B | Method for measuring content of o-chlorobenzyl magnesium chloride | 河北威远生物化工有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-113866292-B | Method for measuring content of o-chlorobenzyl magnesium chloride | 河北威远生物化工有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-113866292-B | Method for measuring content of o-chlorobenzyl magnesium chloride | 河北威远生物化工有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-110590499-B | Continuous reaction device and synthesis method of prothioconazole intermediate | 泰州百力化学股份有限公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-111138461-B | Continuous preparation method of o-chlorobenzyl chloride Grignard reagent | 海利尔药业集团股份有限公司 | 2023-01-20 | — | — | CN | disclosed |
| CN-113866292-A | Method for measuring content of o-chlorobenzyl magnesium chloride | 河北威远生物化工有限公司 | 2021-12-31 | — | — | CN | disclosed |
| CN-206215212-U | A kind of reactor for continuous production RMgBr | 河北兰升生物科技有限公司 | 2017-06-06 | — | — | CN | disclosed |
| CN-106279216-A | A kind of synthesis way of o-chlorobenzyl magnesium chloride | 海正化工南通股份有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-106279216-A | A kind of synthesis way of o-chlorobenzyl magnesium chloride | 海正化工南通股份有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-106279216-A | A kind of synthesis way of o-chlorobenzyl magnesium chloride | 海正化工南通股份有限公司 | 2017-01-04 | — | — | CN | disclosed |
| CN-104011049-A | Pyridopyrimidinone inhibitors of kinases | ABBVIE INC | 2014-08-27 | — | — | CN | disclosed |
| CN-102812003-A | Pyrrolidine Or Thiazolidine Carboxylic Acid Derivatives, Pharmaceutical Composition And Methods For Use In Treating Metabolic Disordersas As Agonists Of G- Protein Coupled Receptor 43 (GPR43) | EUROSCREEN SA | 2012-12-05 | — | — | CN | disclosed |