Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.30 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.30 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.30 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5827578 | 0.77 | LMNA (0.42) | LMNA | |
| SCHEMBL28065149 | 0.73 | CHRM1 (0.43) | LMNAGRIK1 | |
| SCHEMBL11852717 | 0.73 | LMNA (0.39) | LMNA | |
| SCHEMBL1780867 | 0.72 | LMNA (0.37) | LMNA | |
| Carbamic Acid SCHEMBL5387548 | 0.69 | LMNA (0.63) | LMNAALOX15 | |
| SCHEMBL566390 | 0.68 | LMNA (0.39) | LMNA | |
| SCHEMBL9730369 | 0.68 | LMNA (0.39) | LMNA | |
| SCHEMBL2119752 | 0.67 | LMNA (0.40) | LMNAALOX15 | |
| Urea SCHEMBL1377094 | 0.67 | LMNA (0.67) | LMNAALOX15 | |
| SCHEMBL9899630 | 0.67 | LMNA (0.32) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103025356-A | Optimized in vivo delivery systems with endosomolytic agents for nucleic acid conjugates | DNA THERAPEUTICS | 2013-04-03 | — | — | CN | disclosed |