SCHEMBL27898692

SCHEMBL27898692

Cc1ccc2ccn(CC(=O)O)c2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.60
HTR2A P28223 1/20 0.54
HTR2C P28335 1/20 0.54
KMO O15229 2/20 0.48
KDM4E B2RXH2 3/20 0.47
ALDH1A1 P00352 3/20 0.47
POLB P06746 2/20 0.47
MAPT P10636 1/20 0.47
PPARG P37231 3/20 0.47
PPARD Q03181 3/20 0.47
PPARA Q07869 3/20 0.47
HTR7 P34969 1/20 0.46
MCL1 Q07820 2/20 0.45
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
APOBEC3A P31941 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
P2RX7 Q99572 1/20 0.42
PRMT5 O14744 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5537950 0.87 KMT2A (0.60) KMT2AHTR2AHTR2CKDM4EALDH1A1
SCHEMBL16234648 0.84 HTR2A (0.51) KMT2AHTR2AHTR2CKMOKDM4E
SCHEMBL14484449 0.81 KMT2A (0.57) KMT2AKMOKDM4EALDH1A1POLB
SCHEMBL14457826 0.81 KMT2A (0.57) KMT2AKMOKDM4EALDH1A1POLB
SCHEMBL8255076 0.80 KMO (0.56) HTR2AHTR2CKMOHTR7MCL1
SCHEMBL16156155 0.80 KMT2A (0.60) KMT2AHTR2AHTR2CKMOPPARG
SCHEMBL1576364 0.80 KMO (0.72) KMT2AKMOPPARGPPARDPPARA
SCHEMBL2869168 0.80 KMT2A (0.60) KMT2AKMOKDM4EALDH1A1POLB
SCHEMBL29957878 0.80 KMO (0.72) KMT2AKMOPPARGPPARDPPARA
SCHEMBL26683806 0.80 KMT2A (0.60) KMT2AKMOPPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103012274-A Hydroxamic acid compound, and preparation method and use thereof SHANGHAI HUILUN SCIENCE & TECHNOLOGY CO LTD 2013-04-03 CN disclosed