Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.35 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27916438 | 0.83 | MAPT (0.35) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL378363 | 0.83 | SRC (0.50) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL27916456 | 0.81 | SRC (0.34) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL145729 | 0.78 | SRC (0.49) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL25690903 | 0.76 | HTR1A (0.53) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL27898732 | 0.75 | SCN4A (0.39) | ALDH1A1CYP1A2CYP2D6SRCTHRB | |
| SCHEMBL147201 | 0.74 | SRC (0.51) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL11703645 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL2999427 | 0.72 | ALDH1A1 (0.39) | KDM4EALDH1A1MEN1KMT2ACYP1A2 | |
| SCHEMBL14380607 | 0.71 | HTR1A (0.51) | KDM4EALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103038231-A | Modulators of HEC1 activity and methods thereof | TAIVEX THERAPEUTICS INC | 2013-04-10 | — | — | CN | disclosed |