Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Aspartic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.54 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.54 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.52 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.52 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.52 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.52 |
| ▸ | GRM8 | O00222 | 1/20 | 0.52 |
| ▸ | GRM6 | O15303 | 1/20 | 0.52 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.52 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | GRM5 | P41594 | 1/20 | 0.52 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aspartic Acid SCHEMBL27624097 | 1.00 | GRIK1 (0.54) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL28198259 | 0.97 | GRIK1 (0.52) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| D-Aspartate SCHEMBL31235712 | 0.97 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL1526976 | 0.97 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL31673497 | 0.97 | — | — | |
| Aspartic Acid SCHEMBL31070222 | 0.97 | — | — | |
| Aspartic Acid SCHEMBL996424 | 0.97 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| Aspartic Acid SCHEMBL3231 | 0.97 | — | — | |
| Aspartic Acid SCHEMBL11065189 | 0.97 | GRIK1 (0.56) | GRIK1GRIK2GRM1GRM2SLC1A1 | |
| D-Aspartate SCHEMBL145539 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113235146-A | Micro-arc oxidation electrolyte and application method thereof | 江西科技师范大学 | 2021-08-10 | — | — | CN | claimed |
| CN-110301433-A | A kind of pig semen containing trace and REE elements is stored at room temperature agent in vitro | 河南精怡达生物科技有限公司 | 2019-10-08 | — | — | CN | claimed |
| CN-109589298-A | A kind of artemia eggs ghost dispersion liquid and its preparation process and application | 水母娘娘海洋生物科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-109548950-A | The polypeptide and its preparation process in a kind of aurelia source and application | 水母娘娘海洋生物科技有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-107468572-A | One kind polishing isolation breast and preparation method thereof | 漳浦彩露华化妆品有限公司 | 2017-12-15 | — | — | CN | claimed |
| CN-104557286-A | Efficient compound organic acid-based stable ecological fertilizer | INST APPLIED ECOLOGY CAS | 2015-04-29 | — | — | CN | claimed |
| CN-104150971-A | Calcium-reinforced SOD urea fertilizer, preparation method and application thereof | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2014-11-19 | — | — | CN | claimed |
| CN-103059299-B | Compound type MSOD (Models of Superoxide Dismutase) and production process thereof | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2014-01-15 | — | — | CN | claimed |
| CN-103059299-A | Compound type MSOD (Models of Superoxide Dismutase) and production process thereof | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2013-04-24 | — | — | CN | claimed |
| CN-102557798-B | Organic-inorganic compound fertilizer added with SOD (Super Oxygen Dehydrogenise) analogue and production method thereof | BAOYUAN BIO AGRI SHANDONG LTD | 2013-04-03 | — | — | CN | claimed |
| CN-113235146-B | Micro-arc oxidation electrolyte and application method thereof | 江西科技师范大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-113235146-A | Micro-arc oxidation electrolyte and application method thereof | 江西科技师范大学 | 2021-08-10 | — | — | CN | disclosed |
| CN-110772533-A | Multi-ion liquid for treating onychomycosis and preparation method and application thereof | 上海心动能科技有限公司 | 2020-02-11 | — | — | CN | disclosed |
| CN-110301433-A | A kind of pig semen containing trace and REE elements is stored at room temperature agent in vitro | 河南精怡达生物科技有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-107595829-B | A kind of composition for preventing and treating renal osteodystrophy | 贵州亿为康生物科技有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-103059299-A | Compound type MSOD (Models of Superoxide Dismutase) and production process thereof | SHIJIAZHUANG DEV ZONE DESAI CHEMICAL CO LTD | 2013-04-24 | — | — | CN | disclosed |
| CN-102557798-B | Organic-inorganic compound fertilizer added with SOD (Super Oxygen Dehydrogenise) analogue and production method thereof | BAOYUAN BIO AGRI SHANDONG LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-100347180-C | SOD simulated compound with short peptide as ligand and preparation method thereof | BEIJING HUAMEI TIANYI TECHNOLO (CN) | 2007-11-07 | — | — | CN | disclosed |
| CN-1281742-C | Polycondensed amino-acid coordinated SOD simulatives | TEACHER S COLLEGE OF BEIJING U (CN) | 2006-10-25 | — | — | CN | disclosed |
| CN-1803812-A | SOD simulated compound with short peptide as ligand and preparation method thereof | BEIJING HUAMEI TIANYI TECHNOLO (CN) | 2006-07-19 | — | — | CN | disclosed |