Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 7/20 | 0.71 |
| ▸ | WDR48 | Q8TAF3 | 7/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.70 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | USP2 | O75604 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28805460 | 0.92 | CYP1A2 (0.80) | USP1WDR48MEN1KMT2ALMNA | |
| SCHEMBL2583554 | 0.83 | MEN1 (1.00) | USP1WDR48MEN1KMT2ALMNA | |
| SCHEMBL1083874 | 0.82 | MAPK1 (1.00) | USP1WDR48MEN1KMT2ALMNA | |
| SCHEMBL1084183 | 0.80 | MEN1 (0.89) | USP1WDR48MEN1KMT2ALMNA | |
| SCHEMBL12176110 | 0.80 | KMT2A (0.77) | MEN1KMT2ALMNAMAPTCYP1A2 | |
| SCHEMBL2590855 | 0.79 | RAD52 (0.82) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL3459669 | 0.79 | PDE5A (0.85) | USP1WDR48MEN1KMT2ALMNA | |
| SCHEMBL13300124 | 0.78 | CYP1A2 (0.73) | USP1WDR48MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL3643618 | 0.78 | MAPT (0.83) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL3782735 | 0.78 | APP (0.81) | USP1WDR48MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068393-A | Methods and compositions for inhibition of the transitional endoplasmic reticulum atpase | CLEAVE BIOSCIENCES INC CLEAVE | 2013-04-24 | — | — | CN | disclosed |