Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8710708 | 0.78 | KMT2A (0.53) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8716642 | 0.77 | KMT2A (0.51) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL19469362 | 0.76 | KMT2A (0.58) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8713493 | 0.76 | KMT2A (0.58) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL10751931 | 0.76 | ALDH1A1 (0.37) | KMT2AMEN1ALDH1A1POLBPRSS1 | |
| SCHEMBL8711023 | 0.76 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8713770 | 0.76 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8711803 | 0.76 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL10792789 | 0.76 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 | |
| SCHEMBL8711063 | 0.76 | KMT2A (0.50) | KMT2AMEN1PKMCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103951624-B | The manufacturing method of 1,4- diazepan derivatives or its salt | 兴和株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-103068818-B | Novel process for producing isoquinoline derivatives or salts thereof | KOWA CO | 2014-11-19 | — | — | CN | disclosed |
| CN-103951624-A | Production method for isoquinoline derivatives and salts thereof | KOWA CO | 2014-07-30 | — | — | CN | disclosed |
| CN-103068818-A | Novel process for producing isoquinoline derivatives or salts thereof | KOWA CO | 2013-04-24 | — | — | CN | disclosed |