Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 6/20 | 0.38 |
| ▸ | NPFFR2 | Q9Y5X5 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405649 | 0.77 | DPP4 (0.46) | NPFFR1NPFFR2MAOBMAOATAAR1 | |
| SCHEMBL12203625 | 0.69 | HTR2A (0.37) | HTR2AMAOBMAOATAAR1SMN1; SMN2 | |
| SCHEMBL8556244 | 0.68 | SIGMAR1 (0.41) | NPFFR1NPFFR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL75539 | 0.66 | HTR2A (0.43) | HTR2AMAOBMAOATAAR1DPP4 | |
| SCHEMBL3314954 | 0.65 | MAOB (0.65) | HTR2AMAOBMAOATAAR1DPP4 | |
| SCHEMBL27917592 | 0.65 | SMN1; SMN2 (0.48) | LMNADPP4CYP1A2TDP1SMN1; SMN2 | |
| SCHEMBL6125581 | 0.65 | NPFFR1 (0.35) | NPFFR1NPFFR2LMNACYP1A2CYP2C9 | |
| SCHEMBL20130556 | 0.64 | HTR2A (0.42) | HTR2AMAOBMAOATAAR1DPP4 | |
| SCHEMBL8518650 | 0.63 | TDP1 (0.43) | NPFFR1NPFFR2MAOBMAOALMNA | |
| Hydrochloric Acid SCHEMBL9519799 | 0.63 | HTR2A (0.50) | HTR2AMAOBMAOATAAR1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103073502-A | Synthetic method for aromatic cyclourea spiral medicine template and application of template in antineoplastic drugs | WUXI APPTEC CO LTD | 2013-05-01 | — | — | CN | disclosed |