Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3485397 | 0.90 | TDP1 (0.40) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| SCHEMBL23535619 | 0.75 | TDP1 (0.36) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| SCHEMBL16448226 | 0.72 | TDP1 (0.42) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| SCHEMBL8019111 | 0.70 | HTR2B (0.39) | TDP1ALDH1A1HSD17B10CTSDHTR2B | |
| SCHEMBL31236194 | 0.70 | OPRM1 (0.46) | TDP1PTGS2ALDH1A1HSD17B10CTSD | |
| SCHEMBL16162172 | 0.69 | KDM1A (0.43) | TDP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL1531517 | 0.69 | CA12 (0.51) | TDP1CYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL22169154 | 0.68 | ALDH1A1 (0.39) | TDP1PTGS2IDO1CYP1A2CYP3A4 | |
| SCHEMBL3405649 | 0.68 | DPP4 (0.46) | MAOAMAOBSLC6A2HTR2BNPFFR1 | |
| SCHEMBL4059985 | 0.67 | TDP1 (0.43) | TDP1CYP3A4LMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11158150-A | — | — | None | — | — | JP | disclosed |
| JP-H11158150-A | 5-AMINO-1-CYCLOPROPYL-4-OXOQUINOLINE-3-CARBOXYLIC ACID DERIVATIVE AND ITS PREPARATION | IHARA CHEM IND CO LTD | 1999-06-15 | — | — | JP | disclosed |