Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.45 |
| ▸ | PPID | Q08752 | 5/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.45 |
| ▸ | PPIB | P23284 | 4/20 | 0.45 |
| ▸ | PPIG | Q13427 | 3/20 | 0.45 |
| ▸ | PPIA | P62937 | 1/20 | 0.45 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27882615 | 0.87 | PPIB (0.45) | OPRM1PPIDOPRL1PPIBPPIG | |
| SCHEMBL28799932 | 0.86 | PPIB (0.47) | PPIDPPIBPPIGPPIAKCNQ2 | |
| SCHEMBL27900107 | 0.80 | PPID (0.45) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL27900091 | 0.80 | PPID (0.46) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL27900153 | 0.79 | PPID (0.48) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL27900103 | 0.79 | PPIB (0.51) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL27900124 | 0.78 | PPID (0.46) | PPIDPPIBPPIGPPIAMEN1 | |
| SCHEMBL27882621 | 0.74 | PPID (0.45) | PPIDPPIBPPIGPPIA | |
| SCHEMBL27900104 | 0.70 | PPID (0.54) | PPIDPPIBPPIGPPIA | |
| SCHEMBL27900090 | 0.70 | PPID (0.58) | PPIDPPIBPPIGPPIAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102811998-A | Novel cyclophilin inhibitors and uses thereof | INST NAT SANTE RECH MED | 2012-12-05 | — | — | CN | disclosed |