Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIB | P23284 | 5/20 | 0.51 |
| ▸ | PPID | Q08752 | 5/20 | 0.51 |
| ▸ | PPIG | Q13427 | 2/20 | 0.51 |
| ▸ | PPIA | P62937 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28799932 | 0.81 | PPIB (0.47) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL27900107 | 0.81 | PPID (0.45) | PPIBPPIDPPIGPPIANPC1 | |
| SCHEMBL27900153 | 0.80 | PPID (0.48) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL27900089 | 0.79 | OPRM1 (0.45) | PPIBPPIDPPIGPPIAKMT2A | |
| SCHEMBL27900091 | 0.78 | PPID (0.46) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL27900124 | 0.78 | PPID (0.46) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL27882615 | 0.77 | PPIB (0.45) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL27900104 | 0.71 | PPID (0.54) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL27900090 | 0.70 | PPID (0.58) | PPIBPPIDPPIGPPIASMN1; SMN2 | |
| SCHEMBL2044119 | 0.69 | PPID (1.00) | PPIBPPIDPPIGPPIASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102811998-A | Novel cyclophilin inhibitors and uses thereof | INST NAT SANTE RECH MED | 2012-12-05 | — | — | CN | disclosed |