SCHEMBL279002

SCHEMBL279002

CCOC(C)OCc1ccc(N(c2ccc(C)cc2)c2ccc(COC(C)OCC)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
AGXT P21549 2/20 0.40
LMNA P02545 1/20 0.40
FFAR1 O14842 1/20 0.38
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
PARP10 Q53GL7 1/20 0.33
KCNH2 Q12809 1/20 0.33
CYP2C19 P33261 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
MAOB P27338 1/20 0.32
CNR2 P34972 2/20 0.32
CNR1 P21554 1/20 0.32
IDO1 P14902 1/20 0.31
PPARA Q07869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279004 0.95 AGXT (0.37) AGXTLMNAFFAR1CA1CA2
SCHEMBL279477 0.87 LMNA (0.40) LMNACYP2C19ALDH1A1TSHRCNR2
SCHEMBL279018 0.84 PTGS2 (0.39) FFAR1PARP10ALDH1A1NPC1RAB9A
SCHEMBL29599465 0.84 AGXT (0.54) AGXTCA1CA2CA9PARP10
SCHEMBL279298 0.83 IDO1 (0.42) AGXTLMNAALDH1A1CNR2IDO1
SCHEMBL279170 0.80 MAOB (0.41) AGXTNPC1RAB9AMAOBIDO1
SCHEMBL14190104 0.80 PTGS2 (0.43) NPC1RAB9APPARA
SCHEMBL279478 0.77 LMNA (0.32) LMNA
SCHEMBL12677695 0.76 KCNH2 (0.52) AGXTCA1CA2CA9PARP10
SCHEMBL9821507 0.75 LMNA (0.46) AGXTLMNAFFAR1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8426093-B2 photosensitive layer has a charge transferring compound having hole transportation ability; hardening by heating, stable electrical properties FUJI XEROX CO., LTD. (JP) 2013-04-23 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8273517-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-09-25 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-8263299-B2 Multilayer; electroconductive support, photosensitive layer of cured phenolic resin having dynamics hardness and elastic deformation; xerography;thin film with few defects;mechanical strength; stability; high quality images FUJI XEROX CO., LTD. (JP) 2012-09-11 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-20120134713-A1 METHOD OF MANUFACTURING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND PROCESS CARTRIDGE FUJI XEROX CO., LTD. (JP) 2012-05-31 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-8133645-B2 Method of manufacturing electrophotographic photoreceptor, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2012-03-13 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080089712-A1 Image forming apparatus and process cartridge FUJI XEROX CO., LTD. (JP) 2008-04-17 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20080031642-A1 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2008-02-07 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070231721-A1 Electrophotographic photoreceptor, process cartridge, image forming apparatus and coating composition FUJI XEROX CO., LTD. (JP) 2007-10-04 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070065741-A1 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2007-03-22 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed
US-20070003850-A1 Curable resin composition, electrophotographic photoreceptor, process cartridge, and image-forming apparatus FUJI XEROX CO., LTD. (JP) 2007-01-04 US disclosed