Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.67 |
| ▸ | PPARG | P37231 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | CA4 | P22748 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | CA7 | P43166 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resveratrol SCHEMBL27882849 | 1.00 | ALB (0.67) | ALBPPARGALDH1A1MEN1KMT2A | |
| Resveratrol SCHEMBL27900294 | 0.94 | ALB (0.62) | ALBPPARGALDH1A1MEN1KMT2A | |
| Oleic Acid SCHEMBL28802198 | 0.94 | ALB (0.60) | ALBPPARGALDH1A1KMT2AHSD17B10 | |
| Nervonic Acid SCHEMBL27210448 | 0.94 | ALB (0.60) | ALBPPARGALDH1A1KMT2AHSD17B10 | |
| Linoleic Acid SCHEMBL27882839 | 0.91 | PPARG (0.62) | ALBPPARGALDH1A1MEN1KMT2A | |
| Resveratrol SCHEMBL27900295 | 0.88 | PTGS2 (0.61) | ALBPPARGALDH1A1MEN1KMT2A | |
| Resveratrol SCHEMBL28668753 | 0.87 | ALB (0.51) | ALBPPARGALDH1A1MEN1KMT2A | |
| Dodecanoate SCHEMBL27742009 | 0.84 | GPR84 (0.50) | PPARGALDH1A1MEN1KMT2AHSD17B10 | |
| Palmitic Acid SCHEMBL31285120 | 0.84 | ESR1 (0.62) | PPARGALDH1A1MEN1KMT2AHSD17B10 | |
| Palmitic Acid SCHEMBL10942082 | 0.83 | GPR84 (0.71) | PPARGALDH1A1MEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102802656-B | Skin repair compositions comprising a synergistic combination of circadian gene activator and Sirt1 gene activator | ELC MAN LLC | 2014-09-03 | — | — | CN | disclosed |
| CN-102802656-A | Skin repair compositions comprising a synergistic combination of circadian gene activator and Sirt1 gene activator | ELC MAN LLC | 2012-11-28 | — | — | CN | disclosed |