Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | HTR1B | P28222 | 1/20 | 0.30 |
| ▸ | HTR1F | P30939 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022866 | 0.87 | KMT2A (0.48) | KMT2AGPR119BRD4FPR2 | |
| SCHEMBL2597085 | 0.87 | KMT2A (0.48) | KMT2AGPR119BRD4FPR2 | |
| SCHEMBL14918034 | 0.85 | KMT2A (0.37) | HRH3RAB9AKMT2AGPR6HTT | |
| SCHEMBL27918474 | 0.82 | FPR2 (0.38) | GPR6GPR119MCHR1FPR2 | |
| SCHEMBL16011162 | 0.77 | HRH3 (0.34) | HRH3RAB9AKMT2AHTT | |
| SCHEMBL27900696 | 0.76 | MCHR1 (0.34) | L3MBTL1MCHR1FPR2 | |
| SCHEMBL2597221 | 0.74 | GPR119 (0.47) | KMT2AGPR119FPR2 | |
| SCHEMBL14918071 | 0.74 | GPR119 (0.47) | KMT2AGPR119FPR2 | |
| SCHEMBL2596996 | 0.73 | GPR119 (0.48) | KMT2AGPR119FPR2 | |
| SCHEMBL2596997 | 0.73 | GPR119 (0.48) | KMT2AGPR119FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103080101-A | Piperidinyl-substituted lactams as GPR119 modulators | ARRAY BIOPHARMA INC | 2013-05-01 | — | — | CN | disclosed |