SCHEMBL279007

SCHEMBL279007

C=COCCCCOC(=O)OCC(COC(=O)C(=C)C)OC(=O)OCCCCOC=C

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
THRB P10828 1/20 0.33
AKT1 P31749 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL278694 0.83 TSHR (0.42) TSHRPOLBAPEX1HTTTDP1
SCHEMBL757355 0.80 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL5739016 0.80 TSHR (0.61) TSHRPOLBAPEX1HTTTDP1
SCHEMBL6124381 0.78 TSHR (0.34) TSHR
SCHEMBL18822989 0.78 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL18822941 0.78 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2688287 0.78 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL18822943 0.78 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL2689893 0.78 TSHR (0.65) TSHRPOLBAPEX1HTTTDP1
SCHEMBL278845 0.77 TSHR (0.42) TSHRPOLBAPEX1HTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1561791-B1 New ink compositions for ink jet printing AGFA GRAPHICS NV (BE) 2016-03-16 EP disclosed
EP-2053100-B1 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BE) 2015-06-17 EP disclosed
US-8372913-B2 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BG) 2013-02-12 US disclosed
US-8372913-B2 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BG) 2013-02-12 US disclosed
US-20120108746-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2012-05-03 US disclosed
US-20120108746-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2012-05-03 US disclosed
US-8133551-B2 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BE) 2012-03-13 US disclosed
US-8133551-B2 Radiation curable inkjet printing methods AGFA GRAPHICS NV (BE) 2012-03-13 US disclosed
US-20100331478-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2010-12-30 US disclosed
US-20100331478-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2010-12-30 US disclosed
US-RE40847-E1 Ink compositions for ink jet printing AGFA-GEVAERT (BE) 2009-07-14 US disclosed
US-RE40847-E1 Ink compositions for ink jet printing AGFA-GEVAERT (BE) 2009-07-14 US disclosed
WO-2009053283-A1 RADIATION CURABLE INKJET PRINTING METHODS AGFA GRAPHICS NV (BE) 2009-04-30 WO disclosed