Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 13/20 | 0.49 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27900737 | 1.00 | CPB2 (0.49) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL28046409 | 1.00 | CPB2 (0.49) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL16268981 | 0.92 | KDM5A (0.44) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL12985681 | 0.85 | CDK5 (0.48) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL2331925 | 0.85 | CPB2 (0.45) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL2327699 | 0.83 | CPB2 (0.47) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| Hydrochloric Acid SCHEMBL12985270 | 0.83 | CDK5 (0.47) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL28070514 | 0.83 | CPB2 (0.44) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL2330015 | 0.81 | GSK3B (0.43) | CPB2KDM5AKDM2BCDK5CDK5R1 | |
| SCHEMBL13406413 | 0.81 | KDM2B (0.49) | CPB2KDM5AKDM2BCDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801489-A | Cycloalkyl-substituted imidazole derivative | 第三共株式会社 | 2016-07-27 | — | — | CN | disclosed |
| CN-102803226-B | Cycloalkyl-substituted imidazole derivatives | DAIICHI SANKYO Co.,Ltd. (JP) | 2016-05-04 | — | — | CN | disclosed |
| CN-102803226-A | Cycloalkyl-substituted imidazole derivatives | DAIICHI SANKYO CO LTD | 2012-11-28 | — | — | CN | disclosed |