Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 5/20 | 0.44 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.44 |
| ▸ | CPB1 | P15086 | 2/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 3/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331925 | 0.98 | CPB2 (0.45) | CPB2CDK5CDK5R1CPB1KDM2B | |
| SCHEMBL2327699 | 0.97 | CPB2 (0.47) | CPB2CDK5CDK5R1CPB1KDM2B | |
| SCHEMBL12985681 | 0.95 | CDK5 (0.48) | CPB2CDK5CDK5R1CPB1KDM2B | |
| Hydrochloric Acid SCHEMBL12985270 | 0.93 | CDK5 (0.47) | CPB2CDK5CDK5R1CPB1KDM2B | |
| SCHEMBL16268981 | 0.91 | KDM5A (0.44) | CPB2CDK5CDK5R1KDM2BKDM5A | |
| SCHEMBL27900736 | 0.83 | CPB2 (0.49) | CPB2CDK5CDK5R1KDM2BKDM5A | |
| SCHEMBL27900737 | 0.83 | CPB2 (0.49) | CPB2CDK5CDK5R1KDM2BKDM5A | |
| SCHEMBL2330015 | 0.83 | GSK3B (0.43) | CPB2CDK5CDK5R1KDM2BKDM5A | |
| SCHEMBL28046409 | 0.83 | CPB2 (0.49) | CPB2CDK5CDK5R1KDM2BKDM5A | |
| SCHEMBL13406413 | 0.83 | KDM2B (0.49) | CPB2CDK5CDK5R1CPB1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102985439-B9 | IAP BIR domain binding compounds | 制药科学股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102985439-B | IAP BIR domain binding compounds | 制药科学股份有限公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-102985439-A | IAP BIR domain binding compounds | AEGERA THERAPEUTICS INC | 2013-03-20 | — | — | CN | disclosed |