Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 2/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | KLK1 | P06870 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802238 | 0.80 | LMNA (0.42) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL2819101 | 0.75 | LMNA (0.41) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL2819139 | 0.64 | TSHR (0.45) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL6196081 | 0.64 | DAO (0.41) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL2819563 | 0.63 | ALDH1A1 (0.40) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL9684860 | 0.63 | ALDH1A1 (0.53) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL10728124 | 0.63 | ALDH1A1 (0.53) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL9684856 | 0.63 | ALDH1A1 (0.53) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL2330502 | 0.62 | CYP3A4 (0.40) | ALDH1A1LMNAPRNPRECQLRXFP1 | |
| SCHEMBL11235459 | 0.62 | ALDH1A1 (0.53) | ALDH1A1LMNAPRNPRECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101903353-B | Aminopyrazole derivatives | ACTELION PHARMACEUTICALS LTD | 2013-04-10 | — | — | CN | claimed |
| CN-101903353-B | Aminopyrazole derivatives | ACTELION PHARMACEUTICALS LTD | 2013-04-10 | — | — | CN | disclosed |