Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15208952 | 0.84 | PARP1 (0.64) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14934251 | 0.82 | PARP1 (0.57) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Iniparib SCHEMBL29354973 | 0.82 | PARP1 (1.00) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| Iniparib SCHEMBL242006 | 0.82 | PARP1 (1.00) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14934211 | 0.81 | PARP1 (0.56) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17806528 | 0.79 | PARP1 (0.61) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14934242 | 0.79 | PARP1 (0.54) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14934253 | 0.79 | PARP1 (0.54) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL10954211 | 0.79 | PARP1 (0.74) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14934213 | 0.78 | PARP1 (0.42) | PARP1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | claimed |
| CN-103086925-A | Benzoyl urea derivatives having anticancer activity and their preparation method and use | ZHEJIANG HISUN PHARM CO LTD | 2013-05-08 | — | — | CN | disclosed |