Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PDPK1 | O15530 | 3/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 6/20 | 0.38 |
| ▸ | KIT | P10721 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 4/20 | 0.38 |
| ▸ | LCK | P06239 | 3/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 3/20 | 0.36 |
| ▸ | PRKACA | P17612 | 2/20 | 0.36 |
| ▸ | PLK4 | O00444 | 2/20 | 0.36 |
| ▸ | CDK1 | P06493 | 2/20 | 0.36 |
| ▸ | LYN | P07948 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5137240 | 0.79 | SLC6A4 (0.40) | GAAPDPK1MAP2K1AXLKDR | |
| SCHEMBL31586483 | 0.76 | GAA (0.38) | GAAPDPK1MAP2K1AXLKDR | |
| SCHEMBL628649 | 0.74 | PDPK1 (0.66) | GAAPDPK1MAP2K1AXLKDR | |
| SCHEMBL30065304 | 0.74 | PDPK1 (0.66) | GAAPDPK1MAP2K1AXLKDR | |
| SCHEMBL23536586 | 0.72 | RET (0.36) | MAP2K1KDRKITFLT3LCK | |
| SCHEMBL24330092 | 0.71 | HTR1A (0.41) | DYRK1AMEN1POLBKMT2AMKNK2 | |
| SCHEMBL1172460 | 0.71 | GAA (0.47) | GAAPDPK1MAP2K1AXLKDR | |
| SCHEMBL1172394 | 0.71 | GAA (0.56) | GAAPDPK1MAP2K1AXLKDR | |
| SCHEMBL3057752 | 0.71 | KDM4E (0.50) | GAAPDPK1FGFR1AURKAFLT1 | |
| SCHEMBL10076075 | 0.71 | KDR (0.47) | GAAPDPK1MAP2K1AXLKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102822170-A | Substituted N-(1H-indazol-4-yl)imidazo[1, 2-a]pyridine-3- carboxamide compounds as cFMS inhibitors | ARRAY BIOPHARMA INC | 2012-12-12 | — | — | CN | disclosed |