Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 5/20 | 0.34 |
| ▸ | KIT | P10721 | 3/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | LCK | P06239 | 2/20 | 0.31 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | PRKACA | P17612 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.31 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3402451 | 0.86 | GAA (0.44) | GAAPIM1PIM2KDRKIT | |
| SCHEMBL15740705 | 0.83 | PIM1 (0.33) | GAAMAP2K1PDPK1PIM1PIM2 | |
| SCHEMBL31190772 | 0.81 | PIM1 (0.33) | PIM1PIM2NPC1ALDH1A1RAB9A | |
| SCHEMBL15742197 | 0.78 | PIM1 (0.33) | PIM1PIM2KDRKITFLT3 | |
| SCHEMBL29705888 | 0.77 | MAPK8 (0.37) | PIM1PIM2AURKAMAPK8MAPK9 | |
| SCHEMBL30540792 | 0.77 | RAB9A (0.42) | GAAPDPK1PIM1PIM2NPC1 | |
| SCHEMBL27901411 | 0.76 | GAA (0.46) | GAAMAP2K1PDPK1PIM1PIM2 | |
| SCHEMBL17103718 | 0.74 | AURKA (0.33) | PIM1PIM2AURKAPAK4MAPK8 | |
| SCHEMBL19616582 | 0.74 | MAPK8 (0.30) | NPC1RAB9AAURKAAURKBMAPK8 | |
| SCHEMBL19616876 | 0.74 | PRKAB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106014-A1 | COMPOUNDS AND METHODS FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2025-05-22 | — | — | WO | disclosed |