SCHEMBL27901428

SCHEMBL27901428

Cc1cc(CCBr)c(O)c(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.35
TSHR P16473 1/20 0.35
ALOX12 P18054 1/20 0.35
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
CNR2 P34972 3/20 0.32
ATM Q13315 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RARB P10826 4/20 0.31
RARG P13631 4/20 0.31
RARA P10276 3/20 0.31
CNR1 P21554 1/20 0.30
PLA2G4A P47712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11297995 0.88 ALOX12 (0.37) GLATSHRALOX12MEN1KMT2A
SCHEMBL15454103 0.84 RARB (0.40) GLATSHRALOX12MEN1KMT2A
SCHEMBL15613285 0.82 ALOX12 (0.37) GLATSHRALOX12MEN1KMT2A
SCHEMBL27959897 0.82 ALOX12 (0.37) GLATSHRALOX12MEN1KMT2A
SCHEMBL15531154 0.82 ALOX12 (0.37) GLATSHRALOX12MEN1KMT2A
SCHEMBL549445 0.81 MEN1 (0.43) TSHRALOX12MEN1KMT2APOLB
SCHEMBL18969674 0.78 ALOX12 (0.34) GLATSHRALOX12MEN1KMT2A
SCHEMBL3764420 0.77 MEN1 (0.38) TSHRALOX12MEN1KMT2APOLB
SCHEMBL27901400 0.77 MEN1 (0.40) MEN1KMT2APOLBGAAGFER
SCHEMBL27199176 0.77 SELL (0.45) TSHRALOX12MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104379541-A Non-symmetric catalysts containing Salan ligands EXXONMOBIL CHEM PATENTS INC 2015-02-25 CN disclosed
CN-103068831-A Salalen ligands and organometallic complexes UNIV RAMOT 2013-04-24 CN disclosed