SCHEMBL11297995

SCHEMBL11297995

Cc1cc(CBr)c(O)c(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX12 P18054 2/20 0.37
GLA P06280 1/20 0.37
TSHR P16473 1/20 0.37
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
GFER P55789 1/20 0.35
CNR2 P34972 3/20 0.33
HSD17B10 Q99714 2/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RARB P10826 4/20 0.32
RARG P13631 4/20 0.32
RARA P10276 3/20 0.32
CNR1 P21554 1/20 0.31
CASP1 P29466 1/20 0.31
CASP3 P42574 1/20 0.31
CASP7 P55210 1/20 0.31
CASP6 P55212 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27901428 0.88 GLA (0.35) ALOX12GLATSHRMEN1KMT2A
SCHEMBL15454103 0.86 RARB (0.40) ALOX12GLATSHRMEN1KMT2A
SCHEMBL15613285 0.85 ALOX12 (0.37) ALOX12GLATSHRMEN1KMT2A
SCHEMBL27959897 0.85 ALOX12 (0.37) ALOX12GLATSHRMEN1KMT2A
SCHEMBL15531154 0.85 ALOX12 (0.37) ALOX12GLATSHRMEN1KMT2A
SCHEMBL549445 0.84 MEN1 (0.43) ALOX12TSHRMEN1KMT2APOLB
SCHEMBL18969674 0.80 ALOX12 (0.34) ALOX12GLATSHRMEN1KMT2A
SCHEMBL3764420 0.80 MEN1 (0.38) ALOX12TSHRMEN1KMT2APOLB
SCHEMBL27199176 0.79 SELL (0.45) ALOX12TSHRMEN1KMT2APOLB
SCHEMBL13186082 0.78 TSHR (0.38) ALOX12GLATSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104379541-B Non-symmetric catalysts containing Salan ligands 埃克森美孚化学专利公司 2018-02-23 CN disclosed
EP-2880006-B1 NON-SYMMETRIC CATALYSTS COMPRISING SALAN LIGANDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2017-12-20 EP disclosed
US-9695260-B2 Method for producing olefin block polymer using plurality of types of transition metal catalysts SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-04 US disclosed
US-9593194-B2 Method for producing olefin block polymer using group 4 transition metal complex SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-03-14 US disclosed
US-9493587-B2 Metal complexes of salan-type ligands and uses thereof as catalysts for polymerization of alpha-olefins RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2016-11-15 US disclosed
EP-2582710-B1 SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES UNIV RAMOT (IL) 2016-08-10 EP disclosed
CN-103068831-B Salalen part and metal-organic complex 雷蒙特亚特特拉维夫大学有限公司 2016-08-03 CN disclosed
EP-2880006-A2 NON-SYMMETRIC CATALYSTS COMPRISING SALAN LIGANDS ExxonMobil Chemical Patents Inc. (US) 2015-06-10 EP disclosed
US-8957172-B2 Nonsymmetric catalysts comprising salan ligands EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8957172-B2 Nonsymmetric catalysts comprising salan ligands EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-20140275429-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING PLURALITY OF TYPES OF TRANSITION METAL CATALYSTS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-09-18 US disclosed
US-20140163173-A1 METHOD FOR PRODUCING OLEFIN BLOCK POLYMER USING GROUP 4 TRANSITION METAL COMPLEX SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-06-12 US disclosed
US-20140039139-A1 Nonsymmetric Catalysts Comprising Salan Ligands RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-02-06 US disclosed
US-20140039139-A1 Nonsymmetric Catalysts Comprising Salan Ligands RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-02-06 US disclosed
US-20140039139-A1 Nonsymmetric Catalysts Comprising Salan Ligands RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2014-02-06 US disclosed
WO-2014022010-A2 NON-SYMMETRIC CATALYSTS COMPRISING SALAN LIGANDS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-02-06 WO disclosed
EP-2665755-A1 METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS Ramot at Tel Aviv University, Ltd. (IL) 2013-11-27 EP disclosed
US-20130310529-A1 METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2013-11-21 US disclosed
US-20130096271-A1 SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2013-04-18 US disclosed
WO-2012098521-A1 METAL COMPLEXES OF SALAN-TYPE LIGANDS AND USES THEREOF AS CATALYSTS FOR POLYMERIZATION OF ALPHA-OLEFINS RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2012-07-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130096271-A1 SALALEN LIGANDS AND ORGANOMETALLIC COMPLEXES SALL4, SPR, SQLE ALOX12 509/4885GLA 2078/4885TSHR 4690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.