Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 12/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5624217 | 0.86 | TACR1 (0.38) | TACR1KMT2AGPBAR1 | |
| SCHEMBL28034153 | 0.81 | TACR1 (0.43) | TACR1GPBAR1 | |
| SCHEMBL5666117 | 0.80 | MAPT (0.38) | TACR1L3MBTL1GPBAR1 | |
| SCHEMBL14602919 | 0.78 | CETP (0.46) | TACR1GPBAR1 | |
| SCHEMBL13673129 | 0.77 | TACR1 (0.48) | TACR1KMT2AL3MBTL1MEN1 | |
| SCHEMBL7959904 | 0.76 | TACR1 (0.49) | TACR1KMT2AL3MBTL1MEN1 | |
| SCHEMBL15706233 | 0.73 | CETP (0.41) | TACR1KMT2AGPBAR1 | |
| SCHEMBL5802941 | 0.72 | TACR1 (0.52) | TACR1KMT2AL3MBTL1GPBAR1 | |
| SCHEMBL9408665 | 0.72 | TDP1 (0.47) | TACR1KMT2AL3MBTL1MEN1 | |
| SCHEMBL9408639 | 0.72 | TDP1 (0.47) | TACR1KMT2AL3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103102303-B | As the benzyl amine derivative of CETP inhibitor | DR. REDDY'S LABORATORIES LTD. (IN) | 2015-10-28 | — | — | CN | disclosed |
| CN-103102303-A | Benzylamine derivatives as CETP inhibitors | REDDY US THERAPEUTICS INC | 2013-05-15 | — | — | CN | disclosed |