Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.48 |
| ▸ | RXRA | P19793 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.46 |
| ▸ | RXRG | P48443 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959904 | 0.98 | TACR1 (0.49) | TACR1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL9408665 | 0.90 | TDP1 (0.47) | TACR1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL9408639 | 0.90 | TDP1 (0.47) | TACR1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL2475473 | 0.80 | LSS (0.48) | RXRARXRBRXRGCES2MEN1 | |
| SCHEMBL27902017 | 0.77 | TACR1 (0.41) | TACR1L3MBTL1MEN1KMT2A | |
| SCHEMBL31035881 | 0.76 | LSS (0.45) | MEN1KMT2A | |
| SCHEMBL504122 | 0.75 | RXRA (0.68) | TACR1RXRARXRBRXRGLMNA | |
| SCHEMBL18586592 | 0.75 | MEN1 (0.52) | L3MBTL1SERPINE1MEN1KMT2A | |
| SCHEMBL18586316 | 0.75 | SORT1 (0.43) | MEN1KMT2A | |
| SCHEMBL9408647 | 0.75 | RHOC (0.45) | TACR1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923397-B1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES SRL (IT) | 2009-10-28 | — | — | EP | disclosed |
| EP-1923397-A1 | Fluorinated amino acids and peptides | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2008-05-21 | — | — | EP | disclosed |