Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 9/20 | 0.49 |
| ▸ | RXRA | P19793 | 2/20 | 0.47 |
| ▸ | RXRB | P28702 | 2/20 | 0.47 |
| ▸ | RXRG | P48443 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13673129 | 0.98 | TACR1 (0.48) | TACR1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL9408639 | 0.92 | TDP1 (0.47) | TACR1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL9408665 | 0.92 | TDP1 (0.47) | TACR1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL2475473 | 0.81 | LSS (0.48) | RXRARXRBRXRGCES2MEN1 | |
| SCHEMBL504122 | 0.76 | RXRA (0.68) | TACR1RXRARXRBRXRGCES2 | |
| SCHEMBL9408647 | 0.76 | RHOC (0.45) | TACR1L3MBTL1LMNA | |
| SCHEMBL18360373 | 0.76 | L3MBTL1 (0.51) | TACR1RXRARXRBRXRGL3MBTL1 | |
| SCHEMBL10640593 | 0.75 | LMNA (0.65) | TACR1L3MBTL1LMNA | |
| SCHEMBL9408547 | 0.75 | TDP1 (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL16085605 | 0.74 | TACR1 (0.49) | TACR1SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291478-B1 | WEAKENING OR ELIMINATING THE IRRITANT EFFECT OF A PRODUCT HAVING AN IRRITANT EFFECT | L'OREAL (FR) | 2001-09-18 | — | — | US | disclosed |