Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 15/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27714731 | 0.82 | NR3C2 (0.66) | NR3C2GAAMEN1HSP90AA1KMT2A | |
| SCHEMBL6298090 | 0.78 | ESD (0.61) | GAAMEN1HSP90AA1KMT2AEGFR | |
| SCHEMBL31429938 | 0.76 | NR3C2 (0.63) | NR3C2GAAMEN1HSP90AA1KMT2A | |
| SCHEMBL27694764 | 0.76 | NR3C2 (0.64) | NR3C2GAAMEN1HSP90AA1KMT2A | |
| SCHEMBL27997398 | 0.76 | ESD (0.61) | GAAMEN1HSP90AA1KMT2AEGFR | |
| SCHEMBL4254323 | 0.74 | MEN1 (0.87) | NR3C2GAAMEN1HSP90AA1KMT2A | |
| SCHEMBL31429937 | 0.72 | MEN1 (0.82) | NR3C2GAAMEN1HSP90AA1KMT2A | |
| SCHEMBL7586677 | 0.70 | MEN1 (0.53) | NR3C2GAAMEN1HSP90AA1KMT2A | |
| SCHEMBL27955194 | 0.69 | MEN1 (1.00) | NR3C2GAAMEN1HSP90AA1KMT2A | |
| SCHEMBL4592755 | 0.68 | MEN1 (0.67) | NR3C2GAAMEN1HSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101062916-B | Three-substituted 1H-pyrromonazole compound, preparation method, medicament composition and pharmacy use thereof | INST PHARM & TOXICOLOGY AMMS | 2012-12-26 | — | — | CN | disclosed |