Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.53 |
| ▸ | ESD | P10768 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CFTR | P13569 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6298090 | 0.90 | ESD (0.61) | MEN1KMT2AL3MBTL1PRKCZESD | |
| SCHEMBL6292757 | 0.89 | PRKCZ (0.62) | MEN1KMT2AL3MBTL1PRKCZESD | |
| SCHEMBL23052404 | 0.82 | MEN1 (0.73) | MEN1KMT2AL3MBTL1PRKCZEGFR | |
| SCHEMBL395608 | 0.82 | MEN1 (0.73) | MEN1KMT2AL3MBTL1PRKCZEGFR | |
| SCHEMBL27997398 | 0.81 | ESD (0.61) | MEN1KMT2AL3MBTL1PRKCZESD | |
| SCHEMBL6293056 | 0.80 | CA1 (0.56) | MEN1KMT2AL3MBTL1PRKCZEGFR | |
| SCHEMBL6294114 | 0.80 | CA1 (0.56) | MEN1KMT2AL3MBTL1PRKCZESD | |
| SCHEMBL10361833 | 0.79 | MEN1 (0.69) | MEN1KMT2AL3MBTL1PRKCZEGFR | |
| SCHEMBL13680425 | 0.79 | EGFR (0.75) | MEN1KMT2AL3MBTL1PRKCZEGFR | |
| SCHEMBL14338087 | 0.79 | MEN1 (0.69) | MEN1KMT2AL3MBTL1EGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002089799-A2 | USE OF DIHYDROPYRAZOLES TO INCREASE ERYTHROPOIETIN AND VASCULARI ZATION | THE PROCTER & GAMBLE COMPANY (US) | 2002-11-14 | — | — | WO | claimed |