SCHEMBL27902206

SCHEMBL27902206

CC(C)C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.71

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CCKBR P32239 4/20 0.71
ECE1 P42892 5/20 0.67
CTSL P07711 1/20 0.67
CTSS P25774 1/20 0.67
CTSK P43235 1/20 0.67
ACE P12821 3/20 0.66
TP53 P04637 1/20 0.64
MAPT P10636 1/20 0.64
REN P00797 2/20 0.64
ERAP2 Q6P179 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27902208 1.00 CCKBR (0.71) CCKBRECE1CTSLCTSSCTSK
SCHEMBL9787805 0.96 CCKBR (0.71) CCKBRECE1CTSLCTSSCTSK
SCHEMBL30597905 0.96 CCKBR (0.71) CCKBRECE1CTSLCTSSCTSK
SCHEMBL11236250 0.95 CCKBR (0.65) CCKBRECE1CTSLCTSSCTSK
SCHEMBL11236267 0.95 CCKBR (0.65) CCKBRECE1CTSLCTSSCTSK
SCHEMBL9787712 0.94 CCKBR (0.76) CCKBRECE1CTSLCTSSCTSK
SCHEMBL30762270 0.94 CCKBR (0.70) CCKBRECE1CTSLCTSSCTSK
SCHEMBL27902245 0.93 CTSL (0.76) CCKBRECE1CTSLCTSSCTSK
SCHEMBL27871524 0.93 CTSL (0.76) CCKBRECE1CTSLCTSSCTSK
SCHEMBL641549 0.91 CCKBR (0.70) CCKBRCTSLCTSSCTSKTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102807601-B Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof UNIV CAPITAL MEDICAL SCIENCES 2014-02-26 CN disclosed
CN-102807601-A Aminoacyl-tryptophanyl-5-methoxytryptamine and preparation method and application thereof UNIV CAPITAL MEDICAL 2012-12-05 CN disclosed