Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14788895 | 0.86 | TSHR (0.56) | TDP1TSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL14638650 | 0.81 | SIRT6 (0.44) | TDP1TSHRRAB9AL3MBTL1HTT | |
| SCHEMBL20353917 | 0.78 | ABL1 (0.44) | TDP1POLBHTTALDH1A1MEN1 | |
| SCHEMBL1504219 | 0.78 | SIRT6 (0.41) | RAB9AL3MBTL1SIRT6NPC1MAPT | |
| SCHEMBL27886037 | 0.77 | TDP1 (0.73) | TDP1TSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL30007925 | 0.77 | L3MBTL1 (0.61) | RAB9AL3MBTL1LMNAPOLBNPC1 | |
| SCHEMBL15527734 | 0.76 | L3MBTL1 (0.51) | TDP1TSHRRAB9AL3MBTL1POLB | |
| SCHEMBL23980124 | 0.76 | PTK2 (0.59) | TDP1RAB9AL3MBTL1LMNASIRT6 | |
| SCHEMBL28800406 | 0.72 | SIRT6 (0.37) | TDP1TSHRRAB9AL3MBTL1LMNA | |
| SCHEMBL24843516 | 0.70 | NPC1 (0.47) | TDP1TSHRRAB9AL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826333-B | Diamine derivatives | DAIICHI SANKYO CO LTD | 2012-12-26 | — | — | CN | disclosed |