Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 17/20 | 0.69 |
| ▸ | PIK3CB | P42338 | 10/20 | 0.69 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.62 |
| ▸ | PIK3R1 | P27986 | 13/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2813608 | 0.91 | PIK3CA (0.65) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL909478 | 0.83 | PIK3CA (0.81) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL3563102 | 0.83 | PIK3CB (1.00) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL17004656 | 0.82 | PIK3CB (0.94) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL2770694 | 0.81 | PIK3CB (0.92) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL477629 | 0.80 | PIK3CA (0.78) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL477982 | 0.79 | PIK3CA (0.71) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL952221 | 0.79 | PIK3CB (0.83) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL477961 | 0.79 | PIK3CA (0.70) | PIK3CAPIK3CBPIK3CDPIK3R1 | |
| SCHEMBL31157034 | 0.79 | PIK3CB (0.90) | PIK3CAPIK3CBPIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010110685-A2 | PYRIMDDINYL AND 1,3,5-TRIAZINYL BENZIMTOAZOLE SULFONAMIDES AND THEIR USE IN CANCER THERAPY | PATHWAY THERAPEUTICS LIMITED (NZ) | 2010-09-30 | — | — | WO | disclosed |