Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 11/20 | 1.00 |
| ▸ | CA9 | Q16790 | 11/20 | 1.00 |
| ▸ | LMNA | P02545 | 4/20 | 1.00 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.66 |
| ▸ | MAOB | P27338 | 2/20 | 0.66 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.66 |
| ▸ | MAOA | P21397 | 1/20 | 0.66 |
| ▸ | SORD | Q00796 | 1/20 | 0.66 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27442679 | 0.85 | CA12 (0.82) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL26111845 | 0.82 | CA12 (0.70) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL21648248 | 0.80 | CA12 (0.74) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL21648241 | 0.80 | CA12 (1.00) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL21648244 | 0.80 | CA12 (0.74) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL21648245 | 0.80 | CA12 (1.00) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL29570235 | 0.80 | CA12 (0.74) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL3782904 | 0.80 | LMNA (0.67) | CA12CA9LMNAAKR1B1MAOB | |
| SCHEMBL29736952 | 0.80 | CA9 (1.00) | CA12CA9LMNAHSD17B3AKR1B1 | |
| SCHEMBL2987658 | 0.80 | CA9 (1.00) | CA12CA9LMNAHSD17B3AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102846598-A | Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) | GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD | 2013-01-02 | — | — | CN | claimed |
| CN-102846598-A | Application of coumarin in preparing formation inhibitors of advanced glycation end products (AGEs) | GUANGZHOU KANGCHENG PHARMACEUTICAL RES CO LTD | 2013-01-02 | — | — | CN | disclosed |