Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.63 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27904454 | 1.00 | MTNR1A (0.63) | MTNR1AMTNR1BTP53LMNAPOLB | |
| SCHEMBL28149607 | 0.86 | MALT1 (0.58) | MTNR1ATP53LMNAPOLBMALT1 | |
| SCHEMBL28148475 | 0.86 | TP53 (0.57) | MTNR1ATP53LMNAPOLBMALT1 | |
| SCHEMBL15045823 | 0.85 | TP53 (0.60) | MTNR1ATP53LMNAPOLBMALT1 | |
| SCHEMBL9500888 | 0.84 | TP53 (0.56) | MTNR1ATP53LMNAPOLBMALT1 | |
| SCHEMBL4119785 | 0.84 | MTNR1A (0.59) | MTNR1AMTNR1BTP53LMNAPOLB | |
| SCHEMBL22472834 | 0.82 | EPHX2 (0.59) | MTNR1ATP53LMNAPOLBMALT1 | |
| SCHEMBL31715668 | 0.82 | TP53 (0.54) | TP53LMNAPOLBMALT1MAPT | |
| SCHEMBL31277869 | 0.81 | TP53 (0.53) | MTNR1ATP53LMNAPOLBMALT1 | |
| SCHEMBL21810914 | 0.81 | TP53 (0.53) | MTNR1ATP53LMNAPOLBMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103087105-B | Chiral phosphine ligand and comprise the metal catalyst of this part and their application | SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-103087105-A | Chiral phosphine ligand and metal catalyst comprising same and application of chiral phosphine ligand and metal catalyst | SHANGHAI INST ORGANIC CHEM | 2013-05-08 | — | — | CN | disclosed |