Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22472834 | 0.87 | EPHX2 (0.59) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL27904456 | 0.86 | MTNR1A (0.63) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL27904454 | 0.86 | MTNR1A (0.63) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL28148475 | 0.84 | TP53 (0.57) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL15045823 | 0.84 | TP53 (0.60) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL9500888 | 0.83 | TP53 (0.56) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL4119785 | 0.82 | MTNR1A (0.59) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL6502466 | 0.82 | MEN1 (0.55) | MAPTLMNAMTNR1A | |
| SCHEMBL31715668 | 0.81 | TP53 (0.54) | MALT1MAPTTP53LMNAPOLB | |
| SCHEMBL17478440 | 0.80 | MALT1 (0.51) | MALT1MAPTTP53LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106715395-A | 6-amino-5, 6, 7, 8-tetrahydronaphthalen-2-yl or 3-aminochroman-7-yl derivatives as TAAR modulators | 豪夫迈·罗氏有限公司 | 2017-05-24 | — | — | CN | disclosed |