Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 16/20 | 0.48 |
| ▸ | TDO2 | P48775 | 10/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20602751 | 0.70 | IDO1 (0.62) | IDO1TDO2CYP3A4 | |
| SCHEMBL20621023 | 0.70 | IDO1 (0.62) | IDO1TDO2CYP3A4 | |
| SCHEMBL20621024 | 0.70 | IDO1 (0.62) | IDO1TDO2CYP3A4 | |
| SCHEMBL14769012 | 0.70 | CYP19A1 (0.43) | IDO1TDO2CYP3A4CYP11B2 | |
| SCHEMBL2795357 | 0.67 | IDO1 (0.40) | IDO1TDO2CYP3A4 | |
| SCHEMBL19044189 | 0.67 | IDO1 (0.59) | IDO1TDO2CYP3A4 | |
| SCHEMBL29649290 | 0.67 | IDO1 (0.59) | IDO1TDO2CYP3A4 | |
| SCHEMBL2775088 | 0.66 | IDO1 (0.69) | IDO1TDO2CYP3A4CYP11B2NOS3 | |
| SCHEMBL14769100 | 0.66 | CYP19A1 (0.73) | CYP11B2 | |
| SCHEMBL18810584 | 0.66 | IDO1 (0.51) | IDO1TDO2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2435433-B1 | (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES AS FSH RECEPTOR AGONISTS FOR THE TREATMENT OF FERTILITY DISORDERS | MERCK SHARP & DOHME (NL) | 2013-08-28 | — | — | EP | disclosed |
| US-8071587-B2 | (Dihydro)imidazoiso[5,1-A]quinolines | N. V. ORGANON (NL) | 2011-12-06 | — | — | US | disclosed |
| US-20100324021-A1 | (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES | N.V. ORGANON (NL) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324021-A1 | (DIHYDRO)IMIDAZOISO[5,1-A]QUINOLINES | NQO2, IPO5, SCN5A | IDO1 214/4885TDO2 2158/4885CYP3A4 698/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.