Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28800748 | 0.87 | GAA (0.36) | NR1H4MEN1KMT2AMAPTNPC1 | |
| SCHEMBL27888674 | 0.85 | LMNA (0.40) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL27905188 | 0.83 | ITGB1 (0.35) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL2536016 | 0.83 | MEN1 (0.39) | MEN1KMT2ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL27888404 | 0.81 | ALDH1A1 (0.32) | NR1H4MEN1KMT2ALMNAHTT | |
| SCHEMBL27888442 | 0.79 | KMT2A (0.39) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL2532177 | 0.77 | HPN (0.53) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL2536265 | 0.69 | MEN1 (0.46) | MEN1KMT2AHTTMAPTMAPK1 | |
| SCHEMBL2537858 | 0.69 | ALDH1A1 (0.41) | MEN1KMT2ALMNAHTTMAPT | |
| SCHEMBL2530595 | 0.69 | LMNA (0.46) | MEN1KMT2ALMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858746-A | Novel 3,3-dimethyl tetrahydroquinoline derivatives | HOFFMANN LA ROCHE | 2013-01-02 | — | — | CN | disclosed |