Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | TRHR | P34981 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL159687 | 1.00 | OPRK1 (0.44) | OPRK1TRHRHDAC3HDAC11HDAC6 | |
| SCHEMBL159688 | 1.00 | OPRK1 (0.44) | OPRK1TRHRHDAC3HDAC11HDAC6 | |
| SCHEMBL31061201 | 0.91 | OPRK1 (0.45) | OPRK1TRHRHDAC3HDAC11HDAC6 | |
| SCHEMBL22319323 | 0.89 | FOLH1 (0.46) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL22319322 | 0.89 | FOLH1 (0.46) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11173161 | 0.89 | FOLH1 (0.46) | TRHRHDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL11246319 | 0.88 | OPRK1 (0.49) | OPRK1HDAC3HDAC11HDAC6HDAC1 | |
| SCHEMBL31199140 | 0.88 | OPRK1 (0.41) | OPRK1TRHRHDAC3HDAC11HDAC6 | |
| SCHEMBL29713552 | 0.87 | OPRK1 (0.46) | OPRK1TRHRHDAC3HDAC11HDAC6 | |
| SCHEMBL29416863 | 0.87 | OPRK1 (0.46) | OPRK1TRHRHDAC3HDAC11HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103097516-A | Culture medium for eukaryotic cells | FRIESLAND BRANDS BV | 2013-05-08 | — | — | CN | claimed |
| CN-113156096-A | Blood-based biomarkers for diagnosing coronary atherosclerotic disease | 全球基因集团有限责任公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-107427221-B | Blood-based biomarkers for diagnosing coronary atherosclerotic disease | 全球基因集团有限责任公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-107427221-A | Blood-based biomarkers for diagnosing coronary atherosclerotic disease | 全球基因集团有限责任公司 | 2017-12-01 | — | — | CN | disclosed |