SCHEMBL159687

SCHEMBL159687

NC(=O)CC[C@H](NC(=O)[C@@H]1CCC(=O)N1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 2/20 0.44
▸ TRHR P34981 1/20 0.44
▸ HDAC3 O15379 6/20 0.42
▸ HDAC11 Q96DB2 6/20 0.42
▸ HDAC6 Q9UBN7 6/20 0.42
▸ HDAC1 Q13547 5/20 0.42
▸ HDAC2 Q92769 5/20 0.42
▸ HDAC10 Q969S8 5/20 0.42
▸ HDAC8 Q9BY41 5/20 0.42
▸ NCOR2 Q9Y618 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27905689 1.00 OPRK1 (0.44) OPRK1TRHRHDAC3HDAC11HDAC6
SCHEMBL159688 1.00 OPRK1 (0.44) OPRK1TRHRHDAC3HDAC11HDAC6
SCHEMBL31061201 0.91 OPRK1 (0.45) OPRK1TRHRHDAC3HDAC11HDAC6
SCHEMBL22319323 0.89 FOLH1 (0.46) TRHRHDAC3HDAC11HDAC6HDAC1
SCHEMBL22319322 0.89 FOLH1 (0.46) TRHRHDAC3HDAC11HDAC6HDAC1
SCHEMBL11173161 0.89 FOLH1 (0.46) TRHRHDAC3HDAC11HDAC6HDAC1
SCHEMBL11246319 0.88 OPRK1 (0.49) OPRK1HDAC3HDAC11HDAC6HDAC1
SCHEMBL31199140 0.88 OPRK1 (0.41) OPRK1TRHRHDAC3HDAC11HDAC6
SCHEMBL29713552 0.87 OPRK1 (0.46) OPRK1TRHRHDAC3HDAC11HDAC6
SCHEMBL29416863 0.87 OPRK1 (0.46) OPRK1TRHRHDAC3HDAC11HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120041530-A Glutamine peptide with activity of improving alcoholic gastric mucosal injury as well as preparation method and application thereof 中国食品发酵工业研究院有限公司 2025-05-27 — — CN claimed
US-20240315296-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING CJ CHEILJEDANG CORPORATION (KR) 2024-09-26 — — US claimed
EP-4364582-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING CJ Cheiljedang Corporation (KR) 2024-05-08 — — EP claimed
CN-117677302-A Peptide compounds for flavor modulation CJ第一制糖株式会社 2024-03-08 — — CN claimed
WO-2023277549-A1 PEPTIDE COMPOUNDS FOR FLAVOR MODULATING 씨제이제일제당 (주) 2023-01-05 — — WO claimed
US-20130224855-A1 CULTURE MEDIUM FOR EUKARYOTIC CELLS FRIESLANDCAMPINA NEDERLAND HOLDING B.V. (NL) 2013-08-29 — — US claimed
EP-0973518-B1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES UNIV ILLINOIS (US) 2006-03-29 — — EP claimed
EP-0973518-A4 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES UNIV ILLINOIS (US) 2004-05-26 — — EP claimed
US-20020037835-A1 Semi-synthetic studies toward didemnin analogues BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2002-03-28 — — US claimed
US-20010007855-A1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2001-07-12 — — US claimed
EP-0973518-A1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2000-01-26 — — EP claimed
WO-1998017275-A1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1998-04-30 — — WO claimed
US-20250268291-A1 FLAVOR COMPOSITIONS AND SCREENING METHODS FOR IDENTIFYING THE SAME MARS, INCORPORATED (US) 2025-08-28 — — US disclosed
US-12317911-B2 Flavor compositions and screening methods for identifying the same MARS, INCORPORATED (US) 2025-06-03 — — US disclosed
CN-120041530-A Glutamine peptide with activity of improving alcoholic gastric mucosal injury as well as preparation method and application thereof 中国食品发酵工业研究院有限公司 2025-05-27 — — CN disclosed
EP-3768092-B1 FLAVOR COMPOSITIONS AND METHODS FOR PREPARING THE SAME MARS INC (US) 2024-10-02 — — EP disclosed
US-20020037835-A1 Semi-synthetic studies toward didemnin analogues BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2002-03-28 — — US disclosed
US-20010007855-A1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, THE 2001-07-12 — — US disclosed
EP-0973518-A1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2000-01-26 — — EP disclosed
WO-1998017275-A1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 1998-04-30 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010007855-A1 SEMI-SYNTHETIC STUDIES TOWARD DIDEMNIN ANALOGUES FAR1, FASN, GOT1 OPRK1 142/4885TRHR 1651/4885HDAC3 3425/4885
US-20020037835-A1 Semi-synthetic studies toward didemnin analogues FAR1, FASN, GOT1 OPRK1 142/4885TRHR 1651/4885HDAC3 3425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback