Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | NPC1 | O15118 | 2/20 | 0.70 |
| ▸ | RAB9A | P51151 | 2/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16266236 | 0.85 | SMN1; SMN2 (1.00) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL18906003 | 0.85 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL4587893 | 0.85 | ALDH1A1 (0.70) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL6361865 | 0.84 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL11715571 | 0.84 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL6702998 | 0.84 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL31530565 | 0.82 | RAB9A (1.00) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL8372267 | 0.82 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL16266237 | 0.82 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A | |
| SCHEMBL18906006 | 0.82 | ALDH1A1 (0.83) | ALDH1A1SMN1; SMN2PKMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102911124-A | Hydroxy-pyrimidone compound and preparation method and application thereof | UNIV SHANDONG | 2013-02-06 | — | — | CN | claimed |
| CN-102911124-B | Hydroxy pyrimidine ketone compounds and preparation method thereof and application | SHANDONG UNIVERSITY (CN) | 2015-11-25 | — | — | CN | disclosed |
| CN-102911124-A | Hydroxy-pyrimidone compound and preparation method and application thereof | UNIV SHANDONG | 2013-02-06 | — | — | CN | disclosed |