Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5901312 | 1.00 | RECQL (0.49) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| SCHEMBL2792108 | 1.00 | RECQL (0.49) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| SCHEMBL2792110 | 1.00 | RECQL (0.49) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| SCHEMBL5901288 | 0.98 | RECQL (0.50) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| SCHEMBL6288389 | 0.98 | RECQL (0.50) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| SCHEMBL23441772 | 0.94 | RECQL (0.54) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| SCHEMBL10482801 | 0.94 | RECQL (0.54) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL7381167 | 0.90 | RECQL (0.42) | RECQLHDAC8HDAC6LMNASMN1; SMN2 | |
| SCHEMBL1952554 | 0.90 | RECQL (0.44) | RECQLLMNASMN1; SMN2HPGDPOLB | |
| SCHEMBL845078 | 0.90 | RECQL (0.44) | RECQLLMNASMN1; SMN2HPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110065794-A1 | Wrinkle-preventing and improving composition | SHISEIDO COMPANY, LTD. (JP) | 2011-03-17 | — | — | US | disclosed |
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-1908454-A1 | WRINKLE-PREVENTIVE/AMELIORATING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2008-04-09 | — | — | EP | disclosed |
| US-5210266-A | Analgesic enkephalinase inhibitors | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-05-11 | — | — | US | disclosed |
| US-5179125-A | Analgesics | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1993-01-12 | — | — | US | disclosed |
| EP-0318859-A2 | N-substituted mercaptopropanamide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168468-A1 | WRINKLE-PREVENTING AND IMPROVING COMPOSITION | COL1A1, COL2A1, COL14A1 | RECQL 272/4885HDAC8 1808/4885HDAC6 2326/4885 |
| US-20110065794-A1 | Wrinkle-preventing and improving composition | COL1A1, COL2A1, COL14A1 | RECQL 272/4885HDAC8 1808/4885HDAC6 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.