Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | ACACA | Q13085 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 5/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2793669 | 1.00 | FAAH (0.46) | FAAHACACBACACALTA4HF2 | |
| SCHEMBL2792293 | 0.89 | TEAD1 (0.47) | FAAHFFAR1MGLL | |
| SCHEMBL2792710 | 0.82 | ALDH1A1 (0.44) | FAAHMGLL | |
| SCHEMBL20744410 | 0.81 | CHRNB4 (0.52) | F2FFAR1MGLL | |
| SCHEMBL20744482 | 0.81 | CHRNB4 (0.52) | F2FFAR1MGLL | |
| SCHEMBL20744463 | 0.81 | CHRNB4 (0.52) | F2FFAR1MGLL | |
| SCHEMBL20744503 | 0.81 | TEAD1 (0.43) | F2 | |
| SCHEMBL20744395 | 0.81 | TEAD1 (0.43) | F2 | |
| SCHEMBL20744411 | 0.81 | TEAD1 (0.43) | F2 | |
| SCHEMBL1277300 | 0.80 | FAAH (0.73) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010141809-A1 | ARYL-SUBSTITUTED HETEROCYCLIC UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | claimed |
| US-8901111-B2 | Aryl-substituted heterocyclic urea modulators of fatty acid amide hydrolase | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-02 | — | — | US | disclosed |