Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGAV | P06756 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | BDKRB1 | P46663 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789843 | 1.00 | MAPK1 (0.31) | MAPK1ITGB1ITGA4ADRA1APROKR1 | |
| SCHEMBL7900800 | 0.93 | ALOX5AP (0.30) | — | |
| SCHEMBL7898811 | 0.93 | ALOX5AP (0.30) | — | |
| SCHEMBL2789049 | 0.92 | DPP4 (0.34) | MAPK1ITGB1ITGA4ADRA1APROKR1 | |
| SCHEMBL2789767 | 0.92 | DPP4 (0.34) | MAPK1ITGB1ITGA4ADRA1APROKR1 | |
| SCHEMBL2791634 | 0.92 | DPP4 (0.34) | MAPK1ITGB1ITGA4ADRA1APROKR1 | |
| SCHEMBL2789770 | 0.92 | DPP4 (0.34) | MAPK1ITGB1ITGA4ADRA1APROKR1 | |
| SCHEMBL2791931 | 0.89 | SCN9A (0.33) | MAPK1ITGB1ITGA4PROKR1MMEL1 | |
| SCHEMBL2788040 | 0.85 | BTK (0.33) | MAPK1ITGB1ITGA4ADRA1APROKR1 | |
| SCHEMBL2791623 | 0.85 | FPR2 (0.34) | PROKR1ITGB3ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |