Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.30 |
| ▸ | FEN1 | P39748 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 3/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.30 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898811 | 1.00 | ALOX5AP (0.30) | ALOX5APFEN1RENCYP3A4KLK5 | |
| SCHEMBL2790767 | 0.93 | MAPK1 (0.31) | — | |
| SCHEMBL2789843 | 0.93 | MAPK1 (0.31) | — | |
| SCHEMBL7897503 | 0.90 | SCN9A (0.32) | ALOX5APFEN1RENCYP3A4KLK5 | |
| SCHEMBL2789767 | 0.89 | DPP4 (0.34) | RENCYP3A4 | |
| SCHEMBL2789770 | 0.89 | DPP4 (0.34) | RENCYP3A4 | |
| SCHEMBL2791634 | 0.89 | DPP4 (0.34) | RENCYP3A4 | |
| SCHEMBL2789049 | 0.89 | DPP4 (0.34) | RENCYP3A4 | |
| SCHEMBL2813838 | 0.86 | KLK5 (0.36) | ALOX5APFEN1RENCYP3A4KLK5 | |
| SCHEMBL7905913 | 0.86 | CACNA1B (0.35) | RENCYP3A4KLK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |